Part 3 of our video blogs of the 2013 ISSCR annual meeting introduces the fascinating research in cell-based CNS repair done by Dr. Christopher Pröschel at the University of Rochester. You can also find Part 1 and Part 2 in the blog archives.
Dr. Pröschel’s most recent work has focused on using human glial progenitor cells to repair damage to the CNS caused by spinal cord injury. In a 2011 study published in PLoS One, Dr. Pröschel and colleagues describe how human glial precursors were able to restore motor function to spinal cord-injured rats. In our interview, Dr. Pröschel explains the difference between replacement and repair in cell-based regenerative medicine, a theme that fellow spinal cord injury researcher Dr. Aileen Anderson of UC Irvine also frequently touches on. In our video, Dr. Pröschel also has some remarks about direct lineage reprogramming.